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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d80843115b505b548b509d65be13c06f7d5a9a99710baef082c3f14d6ba0a0a' 
  AND token = 'QKnbiKcOvUGc4g2DETtwkUvcdjJmmSGPcY3WT54tQGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables